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Best Boutique Hotels Worldwide Logo

7 of the Best Boutique Hotels in Italy

Our curated boutique hotels in Italy occupy restored 19th-century palazzos with Meyer Davis Studio interiors, canal-side properties with Dorothée Meilichzon design, and lakeside retreats featuring Travertine limestone and cocciopesto plaster. Across seven properties spanning from 32-room intimate stays to 206-room heritage buildings, restored telephone company headquarters by Kengo Kuma sit alongside minimalist spa retreats with volcanic stone features.

Rome's historic neighbourhoods and ancient landmarks anchor the collection, while Venice's canal-side palazzos and secret gardens offer restored elegance. On the shores of Lake Como's mountain-framed waters, minimalist retreats blend contemporary design with alpine panoramas.

Palazzo Talìa occupies a 16th-century palazzo near the Trevi Fountain, the former Collegio del Nazareno school. Studio Luca Guadagnino designed the public spaces and Terrace Suite - the studio's first hospitality project. The 26 rooms are by Mia Home Design Gallery and Laura Feroldi Studio, set above a tropical courtyard.

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Palazzo Talìa lobby with vaulted ceiling, Roman busts on marble plinths and a patterned circular rug
Palazzo Talìa bedroom with iron four-poster bed, walnut credenza and bistro table by the window
Palazzo Talìa suite with striped headboard, emerald velvet armchairs and herringbone parquet floor
Bar della Musa at Palazzo Talìa with mirrored gold tile walls, marble counter and cane bentwood stools
Palazzo Talìa spa with green-tiled vaulted ceiling and experiential plunge pool
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Orient Express La Minerva opened in 2025 as the first standalone Orient Express hotel, in a 17th-century palazzo on Piazza della Minerva, footsteps from the Pantheon. Franco-Mexican artist-architect Hugo Toro designed the 93 rooms and suites, blending Art Deco with nods to the brand's rail heritage.

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 Orient Express La Minerva bedroom with terracotta walls, painted red trim and velvet sofa
Orient Express La Minerva suite with sculpted relief panel, mustard curved sofa and parquet inlay
La Minerva Bar at Orient Express La Minerva with the marble Minerva statue and arched ceiling
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The Hoxton Rome is a stylish boutique hotel located in the elegant Parioli neighbourhood, known for its leafy streets and refined atmosphere. With 192 rooms ranging from Cosy to Roomy categories, each space is thoughtfully designed with bespoke furnishings, marble bathrooms, organic toiletries, and vintage-inspired decor.

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The Hoxton Rome | Boutique Hotel
The Hoxton Rome | Boutique Hotel
The Hoxton Rome | Boutique Hotel
The Hoxton Rome | Boutique Hotel
The Hoxton Rome | Boutique Hotel
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W Rome is a luxury hotel in the stylish Ludovisi neighbourhood, offering 162 rooms and suites with bold colours and modern prints. Many rooms have balconies or terraces with city views, and all are spacious with chic design elements like red velvet curtains, herringbone floors, and marble-clad bathrooms with rain showers.

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W Rome | Boutique Hotel
W Rome | Boutique Hotel
W Rome | Boutique Hotel
W Rome | Boutique Hotel
W Rome | Boutique Hotel
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Mamma Shelter Rome is a fun hotel. You’ll find the rooms to be a playful mix of retro and modern design, featuring unique touches like locally inspired artwork and colourful furnishings.

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Mama Shelter Roma | Boutique Hotel in Rome
Mama Shelter Roma | Boutique Hotel in Rome
Mama Shelter Roma | Boutique Hotel in Rome
Mama Shelter Roma | Boutique Hotel in Rome
Mama Shelter Roma | Boutique Hotel in Rome
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Chapter Roma is a boutique hotel nestled in Rome’s historic Regola neighbourhood, offering 42 rooms designed with an industrial aesthetic that combines sleek metal accents, exposed brick walls, and warm wooden details.

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Chapter Roma
Chapter Roma
Chapter Roma
Chapter Roma
Chapter Roma
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Six Senses Rome is a five-star retreat with 96 rooms and suites, housed in a beautifully restored palazzo. The decor is minimalist, showcasing natural materials such as Travertine limestone, oak wood, and cocciopesto plaster—a respectful nod to ancient Roman craftsmanship.

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Six Senses Rome
Six Senses Rome
Six Senses Rome
Six Senses Rome
Six Senses Rome
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Il Palazzo Experimental is a boutique hotel overlooking the Giudecca canal, in the heart of Venice. The hotel offers 32 rooms and suites, bathed in natural light with views of the Canal della Giudecca from the Palazzo’s front, or a secret garden in the back.

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Il Palazzo Experimental | Boutique Hotel in Venice
Il Palazzo Experimental | Boutique Hotel in Venice
Il Palazzo Experimental | Boutique Hotel in Venice
Il Palazzo Experimental | Boutique Hotel in Venice
Il Palazzo Experimental | Boutique Hotel in Venice
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Il Sereno Lago di Como is a five-star boutique hotel located on the shores of Lake Como. Each of its 40 spacious suites boasts floor-to-ceiling windows with stunning views of the lake and surrounding mountains with sleek, minimalist decor in a neutral colour palette.

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Il Sereno Lago di Como, a five-star hotel in Lake Como.
Il Sereno Lago di Como, a five-star hotel in Lake Como.
Il Sereno Lago di Como, a five-star hotel in Lake Como.
Il Sereno Lago di Como, a five-star hotel in Lake Como.
Il Sereno Lago di Como, a five-star hotel in Lake Como.
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Nomos Hotel occupies a former Franciscan monastery in Rome's Regola district, adjacent to the church of San Paolo alla Regola. Italian artisan-designer Henry Timi (in his first hospitality project) led the conversion, applying what he calls 'material minimalism' across plaster, terracotta, terrazzo and travertine.

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Casa Monti opened in summer 2024 as the first Italian hotel from the Kampf family, the small group behind La Fantaisie in Paris and Cœur de Megève. The 36 rooms occupy a historic Roman building on Via Panisperna in Monti, the city's oldest creative quarter, with interiors by Parisian designer Laura Gonzalez.

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